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SIGMA INVESTMENT HOUSE HEALTHCARE, FI

Category
Latest period
H2 2025
Positions
81

Portfolio as of 2025-12-31. Source: periodic filing with the CNMV. View original filing (PDF)

Full portfolio

Every position in the latest periodic filing, largest weight first. Aggregates ("other equities...") are baskets of small positions the filing itself does not break out line by line.

81
Company Type Country Weight Price
ACCIONES|Lilly (Eli) & Co. US5324571083 · USD Renta Variable Cotizada US 9.57%
ACCIONES|Johnson US4781601046 · USD Renta Variable Cotizada US 6.19%
BANCO INVERSIS, S.A. ES0000012O67 · EUR Adquisicion Temporal Activos ES 5.09%
ACCIONES|AbbVie Inc US00287Y1091 · USD Renta Variable Cotizada US 4.69%
ACCIONES|Unitedhealth Group US91324P1021 · USD Renta Variable Cotizada US 3.48%
ACCIONES|ROCHE HOLDING CH0012032048 · CHF Renta Variable Cotizada CH 3.39%
ACCIONES|AstraZeneca Group GB0009895292 · GBP Renta Variable Cotizada GB 3.37%
ACCIONES|Merck & Co. Inc. US58933Y1055 · USD Renta Variable Cotizada US 3.07%
ACCIONES|NOVARTIS AG-REG SHS US66987V1098 · USD Renta Variable Cotizada US 3.07%
ACCIONES|Thermo Electron Corp US8835561023 · USD Renta Variable Cotizada US 2.54%
ACCIONES|Abbott Laboratories US0028241000 · USD Renta Variable Cotizada US 2.54%
ACCIONES|Intuitive Surgical US46120E6023 · USD Renta Variable Cotizada US 2.45%
ACCIONES|Lonza Group AG CH0013841017 · CHF Renta Variable Cotizada CH 2.27%
ACCIONES|Amgen Inc. US0311621009 · USD Renta Variable Cotizada US 2.05%
ACCIONES|Novo-Nordisk DK0062498333 · DKK Renta Variable Cotizada DK 1.91%
ACCIONES|Gilead Sciences Inc US3755581036 · USD Renta Variable Cotizada US 1.84%
ACCIONES|Danaher Corp US2358511028 · USD Renta Variable Cotizada US 1.76%
ACCIONES|Pfizer Inc US7170811035 · USD Renta Variable Cotizada US 1.76%
ACCIONES|Accs. Boston Scienti US1011371077 · USD Renta Variable Cotizada US 1.62%
ACCIONES|Medtronic INC IE00BTN1Y115 · USD Renta Variable Cotizada IE 1.51%
ACCIONES|Stryker Corporation US8636671013 · USD Renta Variable Cotizada US 1.48%
ACCIONES|Fagron BE0003874915 · EUR Renta Variable Cotizada BE 1.41% 22.35 EUR
ACCIONES|Vertex Pharmaceutica US92532F1003 · USD Renta Variable Cotizada US 1.41%
ACCIONES|Bristol - Myers Sqi US1101221083 · USD Renta Variable Cotizada US 1.39%
ACCIONES|Sanofi - Synthelabo FR0000120578 · EUR Renta Variable Cotizada FR 1.32%
ACCIONES|McKesson Corporation US58155Q1031 · USD Renta Variable Cotizada US 1.26%
ACCIONES|GlaxoSmithKline PLC GB00BN7SWP63 · GBP Renta Variable Cotizada GB 1.24% 1918.50 GBp
ACCIONES|Grifols ES0171996095 · EUR Renta Variable Cotizada ES 1.07%
ACCIONES|HCA Inc US40412C1018 · USD Renta Variable Cotizada US 1.06%
ACCIONES|Regeneron Pharmaceut US75886F1075 · USD Renta Variable Cotizada US 0.98%
ACCIONES|Elevance Health Inc US0367521038 · USD Renta Variable Cotizada US 0.97% 400.54 USD
ACCIONES|Cigna Corp US1255231003 · USD Renta Variable Cotizada US 0.94%
ACCIONES|CVS US1266501006 · USD Renta Variable Cotizada US 0.87%
ACCIONES|Amerisourcebergen US03073E1055 · USD Renta Variable Cotizada US 0.79%
ACCIONES|Becton Dickinson US0758871091 · USD Renta Variable Cotizada US 0.74%
ACCIONES|Hoya Corp JP3837800006 · JPY Renta Variable Cotizada JP 0.72%
ACCIONES|Zoetis US98978V1035 · USD Renta Variable Cotizada US 0.69%
ACCIONES|Takeda Chemical Ind. JP3463000004 · JPY Renta Variable Cotizada JP 0.69%
ACCIONES|IdexLab US45168D1046 · USD Renta Variable Cotizada US 0.68%
ACCIONES|Cardinal Health Inc US14149Y1082 · USD Renta Variable Cotizada US 0.68%
ACCIONES|ARGENX SE NL0010832176 · EUR Renta Variable Cotizada NL 0.67%
ACCIONES|Edwards Lifesciences US28176E1082 · USD Renta Variable Cotizada US 0.67%
ACCIONES|Alnylam Pharmaceutic US02043Q1076 · USD Renta Variable Cotizada US 0.65%
ACCIONES|Agilent Technologies US00846U1016 · USD Renta Variable Cotizada US 0.52%
ACCIONES|UCB SA BE0003739530 · EUR Renta Variable Cotizada BE 0.52%
ACCIONES|Accs. Teva Pharmaceu US8816242098 · USD Renta Variable Cotizada US 0.51% 37.34 USD
ACCIONES|IQVIA Hold Inc US46266C1053 · USD Renta Variable Cotizada US 0.50%
ACCIONES|Chugai Pharmaceu Co JP3519400000 · JPY Renta Variable Cotizada JP 0.49%
ACCIONES|Resmed Inc US7611521078 · USD Renta Variable Cotizada US 0.47%
ACCIONES|Veeva Systems Inc-A US9224751084 · USD Renta Variable Cotizada US 0.47%
ACCIONES|GE HealthCare Techno US36266G1076 · USD Renta Variable Cotizada US 0.46%
ACCIONES|Mettler-Toledo Inter US5926881054 · USD Renta Variable Cotizada US 0.41%
ACCIONES|Human Inc US4448591028 · USD Renta Variable Cotizada US 0.40%
ACCIONES|Descom Inc US2521311074 · USD Renta Variable Cotizada US 0.36%
ACCIONES|Biogen Idec Inc US09062X1037 · USD Renta Variable Cotizada US 0.35%
ACCIONES|STERIS PLC IE00BFY8C754 · USD Renta Variable Cotizada IE 0.34%
ACCIONES|Astellas Pharma Inc JP3942400007 · JPY Renta Variable Cotizada JP 0.33%
ACCIONES|Atrys Health SA ES0105148003 · EUR Renta Variable Cotizada ES 0.32%
ACCIONES|Otsuka Holdings Co L JP3188220002 · JPY Renta Variable Cotizada JP 0.32%
ACCIONES|Waters Corp US9418481035 · USD Renta Variable Cotizada US 0.30%
ACCIONES|Centene Corp US15135B1017 · USD Renta Variable Cotizada US 0.30%
ACCIONES|Labcorp Holdings Inc US5049221055 · USD Renta Variable Cotizada US 0.30%
ACCIONES|Illumina Inc US4523271090 · USD Renta Variable Cotizada US 0.29%
ACCIONES|Genmab A/S DK0010272202 · DKK Renta Variable Cotizada DK 0.29%
ACCIONES|West Pharmaceutical US9553061055 · USD Renta Variable Cotizada US 0.28%
ACCIONES|TERUMO CORP JP3546800008 · JPY Renta Variable Cotizada JP 0.27%
ACCIONES|Mer DE0006599905 · EUR Renta Variable Cotizada DE 0.26%
ACCIONES|Zimmer Holdings Inc US98956P1021 · USD Renta Variable Cotizada US 0.26%
ACCIONES|Hologic Inc US4364401012 · USD Renta Variable Cotizada US 0.25%
ACCIONES|Accs. Cooper Industr US2166485019 · USD Renta Variable Cotizada US 0.22%
ACCIONES|Olympus Optical Co L JP3201200007 · JPY Renta Variable Cotizada JP 0.21%
ACCIONES|Siemens AG DE000SHL1006 · EUR Renta Variable Cotizada DE 0.20%
ACCIONES|Biomarin Pharmaceuti US09061G1013 · USD Renta Variable Cotizada US 0.16%
ACCIONES|Align Technology Inc US0162551016 · USD Renta Variable Cotizada US 0.16%
ACCIONES|Coloplast DK0060448595 · DKK Renta Variable Cotizada DK 0.15%
ACCIONES|Molina Healthcare In US60855R1005 · USD Renta Variable Cotizada US 0.14%
ACCIONES|Baxter Internacional US0718131099 · USD Renta Variable Cotizada US 0.13%
ACCIONES|MODERNA INC US60770K1079 · USD Renta Variable Cotizada US 0.13%
ACCIONES|Avantor Inc US05352A1007 · USD Renta Variable Cotizada US 0.11%
ACCIONES|GRAIL INC US3847471014 · USD Renta Variable Cotizada US 0.03%
ACCIONES|Veralto Corp US92338C1036 · USD Renta Variable Cotizada US 0.00%

This period's moves

H2 2025 vs H1 2025 (estimated)

New: 4 Exits: 3 Increases: 5 Cuts: 12
+ BANCO INVERSIS, S.A.

Enters the portfolio at 5.09% weight.

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+ ACCIONES|Lonza Group AG

Enters the portfolio at 2.27% weight.

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+ ACCIONES|Fagron

Enters the portfolio at 1.41% weight.

Fagron NV, a pharmaceutical compounding company, delivers personalized pharmaceutical care to hospitals, pharmacies, clinics, patients, and worldwide. It operates through three segments: Essentials, Brands, and Compounding Services. The company's products include DiluCap, a line of excipients to compound every capsule formulation; DiluTab, for Cardiology and Primary care application; Imuno TF Complex helps in regulation of immune responses; Pigmerise, a natural phytocomplex for hypopigmentation disorders, such as vitiligo; Pentravan uses for avoiding first-pass metabolism and preventing gastrointestinal erosion; Nourisil MD, a first line therapy for prevention and treatment of scars ang keloids; Neogen, a line of hair care products; TrichoConcept used to treat alopecia; Fagron Advanced Derma for basic skincare, compound pharmaceutical treatment, and individualized dermatological care; SyrSpend SF that provides pharmaceutical stability, dosage consistency, and patient comfort; and Cleoderm, a topical cream used for the compounding of personalized dermatological treatments. It also offers education and professional development of prescribers, hospitals, and pharmacists through the Fagron Academy. The company was formerly known as Arseus NV and changed its name to Fagron NV in January 2015. Fagron NV was founded in 1990 and is based in Nazareth, Belgium.

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+ ACCIONES|Grifols

Enters the portfolio at 1.07% weight.

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− ACCIONES|IncytCor

Leaves the portfolio; it was 1.72% of weight.

− ACCIONES|ESSILOR

Leaves the portfolio; it was 1.31% of weight.

− ACCIONES|Biontech SE

Leaves the portfolio; it was 1.30% of weight.

▲ ACCIONES|Johnson

Goes from 5.14% to 6.19%.

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▲ ACCIONES|Lilly (Eli) & Co.

Goes from 8.67% to 9.57%.

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▲ ACCIONES|Thermo Electron Corp

Goes from 2.09% to 2.54%.

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▲ ACCIONES|AstraZeneca Group

Goes from 3.01% to 3.37%.

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▲ ACCIONES|Merck & Co. Inc.

Goes from 2.74% to 3.07%.

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▼ ACCIONES|Novo-Nordisk

Goes from 3.09% to 1.91%.

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▼ ACCIONES|Abbott Laboratories

Goes from 3.30% to 2.54%.

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▼ ACCIONES|Stryker Corporation

Goes from 2.06% to 1.48%.

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▼ ACCIONES|Accs. Boston Scienti

Goes from 2.19% to 1.62%.

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▼ ACCIONES|Unitedhealth Group

Goes from 3.98% to 3.48%.

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▼ ACCIONES|Zoetis

Goes from 1.05% to 0.69%.

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▼ ACCIONES|Cigna Corp

Goes from 1.29% to 0.94%.

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▼ ACCIONES|Vertex Pharmaceutica

Goes from 1.68% to 1.41%.

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▼ ACCIONES|Intuitive Surgical

Goes from 2.72% to 2.45%.

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▼ ACCIONES|Elevance Health Inc

Goes from 1.22% to 0.97%.

Elevance Health, Inc., together with its subsidiaries, operates as a health benefits company in the United States. The company operates in four segments: Health Benefits, CarelonRx, Carelon Services, and Corporate & Other. It offers a variety of health plans and services to individual, employer group risk-based and fee-based, BlueCard, Medicare, Medicaid, and FEP members; health products; a broad array of fee-based administrative managed care services; and specialty and other insurance products and services, such as stop loss, dental, vision, and supplemental health insurance benefits. The company also operates in the pharmacy services business; and markets and offers pharmacy services, including home delivery and specialty pharmacies, claims adjudication, formulary management, pharmacy networks, rebate administration, a prescription drug database, and member services, as well as infusion services and injectable therapies through ambulatory infusion centers. In addition, it provides healthcare related services and capabilities, including specialty care enablement and utilization management support for specialized clinical domains; behavioral health and comprehensive care management services; palliative care services and management; virtual care; and payment integrity, subrogation, clinical data exchange through its HealthOS platform, research and data, reporting and clinical analytics, information technology, and business process support services, as well as manages home health, post-acute institutional management, and durable medical equipment costs; and supports plans in managing home and community-based services. The company provides its services under the Anthem Blue Cross and Blue Shield, Wellpoint, and Carelon brands. The company was formerly known as Anthem, Inc. and changed its name to Elevance Health, Inc. in June 2022. Elevance Health, Inc. was incorporated in 2001 and is based in Indianapolis, Indiana.

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▼ ACCIONES|Veeva Systems Inc-A

Goes from 0.69% to 0.47%.

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▼ ACCIONES|Pfizer Inc

Goes from 1.97% to 1.76%.

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Fixed income

Declared FI exposure
2.0 M €
% of portfolio
5.1%
Positions
1
Issuers
0
Sovereign: 0 € Corporate: 0 € Repos / treasury management: 2.0 M €

Maturity ladder

Observed contractual maturity of each position, repos excluded. Matured/≤3 months includes bonds maturing in the first days after the period close.

Maturity Positions Exposure %
Matured or ≤3 months 0 0 € 0.0%
3-6 months 0 0 € 0.0%
6-12 months 0 0 € 0.0%
1-2 years 0 0 € 0.0%
2-5 years 0 0 € 0.0%
5-10 years 0 0 € 0.0%
> 10 years 0 0 € 0.0%
Unknown 0 0 € 0.0%

Disclaimer

This is not financial advice. The portfolio comes from the periodic report the fund files with the CNMV and lags the real close of the period: it is a snapshot of the end of each half-year, not a real-time portfolio.